8.05.2010

Urticaria-What's The Difference Between Acute & chronic

Acute Urticaria is is normally diagnosed if it has been present for less than 6 weeks. The symptoms of acute Urticaria usually go within a couple of days to a few weeks.

Chronic Urticaria is defined as Urticaria that has been continuously or intermittently present for at over 6 weeks, chronic Urticaria can persist for years in some cases, with symptoms ranging from itchy bumps to inflamed skin lesions (weal's), and in more serious cases can be accompanied by something called Angiodema, which causes severe swelling.

Urticaria occurs following release of histamine in the skin which causes the small blood vessels near the skin's surface (mast cells) to leak fluid, hence causing the irritation and swelling consistent with the condition.

Urticaria has four major mechanisms. Most commonly, it is a manifestation of acute immunoglobulin E (IgE)-mediated hypersensitivity with histamine and other vasoactive peptides released from mast cells and basophils.

Non immunologic Urticaria occurs when an exogenous substance results in mast cell de granulation either by direct stimulation of the mast cell or by unknown mechanisms such as underlying conditions, aspirin and other non steroidal anti-inflammatory drugs (NSAIDs) are also thought to cause Urticaria by a non-mast cell mechanism,

Some of the causes of Urticaria may be:

1.Allergens.
2.Environmental factors.(for example, heavy metal in drinking water)
3.Drugs.(due to toxicity build up in the body).
4.Alcohol.
5.Emotional factors( stress).
6.Underlying viral and bacterial conditions (associated with the gut)
7.Chemicals and solvents
8.Food intolerances
9.Food additives, colourings and preservatives.
10.Smoking (due to the release of excess free radicals in to the blood stream)

Symptoms of Urticaria

1.Rash (swelling, weal's, bumps)
2.Itchiness
3.Stress.

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